AI-Powered DICOM Annotation on Your Mac.
Fully local. Fully private. Powered by Gemma 4 E4B running on Apple Silicon via MLX. Analyze images, detect structures, describe ROIs — no cloud, no uploads.
macOS 14.0+ (Sonoma) · Apple Silicon · 16GB+ RAM recommended


DICOM Viewer Meets On-Device AI
Everything you need in a medical image viewer, plus AI annotation that runs entirely on your machine.
SwiftUI + Metal Native App
Native Performance with SwiftUI & Metal
Built with SwiftUI and Metal. No Electron, no web views — just native macOS speed with GPU-accelerated rendering. Custom pure-Swift DICOM parser ensures the first image appears before the rest of the study finishes loading.
- SwiftUI-based native macOS interface
- Metal GPU-accelerated rendering
- Custom pure-Swift DICOM parser for fast loading
- Background loading with instant first image display
On-Device AI Annotation
On-Device AI Annotation with Gemma 4
Google's Gemma 4 vision-language model runs locally on Apple Silicon GPU via MLX. Analyze images, detect structures, describe ROIs, identify abnormalities — no internet required, no cloud uploads, 100% private.
- Gemma 4 E4B 4-bit quantized model running locally
- Full image analysis with anatomical structure detection
- Natural language ROI descriptions on selection
- Abnormality detection with severity and confidence scores
AI Analysis Modes
Four modes powered by Gemma 4 for different workflows.
Only clinically significant findings. Maximum 3 bounding boxes for quick assessment.
All visible anatomical structures labeled and boxed. Minimum 3 structures for comprehensive mapping.
Pathological findings only. Up to 2 abnormalities with severity and confidence.
Labeled anatomy for learning. 3-5 structures with detailed descriptions.
Get Started
Up and running in seconds.
Download for macOS
- 1.Download the latest release, open the DMG, and drag to Applications.
- 2.Signed and notarized — no Gatekeeper warnings.
- 3.AI model downloads automatically on first use (~4.5GB).
Build from Source (optional)
# Clone and build
git clone https://github.com/Essential-Citronnier/ODV-Annotate.git
cd ODV-Annotate
./scripts/package_app.sh
Built by Researchers
Built on Prof. JoonNyung Heo's OpenDicomViewer open source. MIT licensed open-source project.
JoonNyung Heo, MD, PhD
Original OpenDicomViewer Author
Assistant Professor of Neurology, Yonsei University College of Medicine. Stroke neurologist & neurointerventionist. MIT Technology Review Innovators Under 35 (Korea, 2021).
Daeseong Kim, MD
AI Annotation Developer
Research Scientist, Computational & Translational Oncology. Yonsei University College of Medicine (MD, 2025, Summa Cum Laude). First-author in Clin Mol Hepatol. Built the Gemma 4 E4B on-device annotation layer.

Get Started Now
OpenDicomViewer-Annotate is open source under the MIT License. Built with SwiftUI, Metal, and Gemma 4.